There is clearly a very strong need to develop an antidote for these two particular medications and any other medications that act through a similar mechanism.” Xarelto and Eliquis are the top two prescribed anticoagulants in the United States. The two medications that I’m specifically talking about, Xarelto and Eliquis, to date have no antidote. And Pradaxa which is a novel oral anticoagulant but works through a different mechanism than Xarelto or Eliquis, it also has an antidote that just got released to the market about a year ago.
Contrast that to Coumadin: if you come in with a bleeding event we can give you Vitamin K which is a typical antidote that’s used to try to reverse Coumadin immediately. Now medication specifically Xarelto and Eliquis do not have an antidote available to them as of yet. Some examples are Xarelto, Eliquis or Pradaxa. DRUG BACKGROUND: Rishi Anand, MD, Medical Director for the Electrophysiology Laboratory at Holy Cross Hospital explained the difference between old and new blood thinners, and why a new antidote is necessary: “Coumadin is a generic blood thinner that has been on the market for many years and in the last decade there have been new comers to the market which we call novel oral anticoagulants.
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